A recessive captain confines herself in her quarters as she evaluates her decision five years ago when they were first flung into the Delta Quadrant. Janeway reflects on the decision she had made to destroy the Caretaker's array, feeling responsible for her crew being stranded in the Delta Quadrant and landing in this current void in space.

There's a sudden emergence of a dangerous new lifeform aboard Voyager after The Doctor's 29th century mobile emitter technology mysteriously fuses with Seven of Nine's Borg nanoprobes, creating an advanced male Drone. He hails the Collective and the Voyager crew once again has to deal with the Borg. But this time, they have a 29th century Borg to help Voyager defeat the Borg Sphere that has arrived.